
Chronic joint pain, tendon injuries, and soft tissue damage are among the most undertreated conditions in conventional medicine. Steroid injections can reduce inflammation temporarily, but they do nothing to rebuild the tissue that's been worn down. Prolozone therapy does something different: it regenerates.
Prolozone is an injection-based therapy that combines medical ozone gas with procaine (a local anesthetic) and targeted nutrient cofactors including B12, homeopathic anti-inflammatories, and joint-supportive minerals. This combination is injected directly into the affected joint, tendon, ligament, or soft tissue — stimulating the body's repair mechanisms at the cellular level.
Developed by Dr. Frank Shallenberger, prolozone has shown remarkable results in patients who have tried physical therapy, cortisone shots, and even considered surgery — often producing lasting relief where other approaches have plateaued.
• Knee, hip, shoulder, and ankle joint pain
• Degenerative joint disease and osteoarthritis
• Chronic back and neck pain
• Rotator cuff injuries and tendinopathies
• Plantar fasciitis
• Sports injuries and ligament laxity
• Jaw (TMJ) dysfunction
• Post-surgical pain and scar tissue
"When you stop suppressing pain and start rebuilding what created it, the body often exceeds every expectation."
Step 1
Evaluation — We review your imaging, symptom history, and functional status to identify the specific joints and tissues to target.
Step 2
Injection Protocol Design — The prolozone formula is customized based on the joint involved, degree of degeneration, and your inflammatory status.
Step 3
Injection — The area is cleansed and procaine is administered for comfort. The prolozone solution is then injected precisely into the target tissue. The procedure is quick and well-tolerated by most patients.
Step 4
Healing Response — Ozone stimulates fibroblast proliferation and collagen synthesis — the building blocks of repair. You may experience mild soreness for 24–48 hours as the healing cascade begins.
Step 5
Repeat & Reassess — Most patients require a series of 3–6 injections spaced 1–2 weeks apart. Many report significant improvement by the second or third session.